Publications by Member

Eric Berns

Eric’s Publications:

Research Assistant Professor

Lab Member Since 2013

 

 

  1. Temporal Sampling of Enzymes from Live Cells by Localized Electroporation and Quantification of Activity by SAMDI Mass Spectrometry.  P. Mukherjee, E. J. Berns, C. A. Patino, E. H. Moully, L. Chang, S. S. P. Nathamgari, J. A. Kessler, M. Mrksich and H. D. Espinosa  Small, 2020, 2000584. [PDF]
  2. Label-Free Assay of Protein Tyrosine Phosphatase Activity in Single Cells.  E. H. Moully, E. Berns and M. Mrksich  Anal. Chem., 2019, 91, 13206-13212. [PDF]
  3. Exploration of the Nanomedicine-Design Space With Highthroughput Screening and Machine Learning.  G. Yamankurt, E. J. Berns, A. Xue, A. Lee, N. Bagheri, M. Mrksich and C. A. Mirkin  Nat. Biomed. Eng., 2019, 3, 318-327. [PDF]
  4. Traceless Immobilization of Analytes for High Throughput Experiments with SAMDI Mass Spectrometry.  Helal, K.Y., Alamgir, A., Berns, E.J. and Mrksich, M.  J. Am. Chem. Soc., 2018, 140, 8060-8063. [PDF] 
  5. Combining SAMDI Mass Spectrometry and Peptide Arrays to Profile Phosphatase Activities.  L. C. Szymczak, C.-F. Huang, E. J. Berns and M. Mrksich  Methods in Enzymology, 2018, 607, 389-403. [PDF]
  6. In vivo migration of endogenous brain progenitor cells guided by an injectable peptide amphiphile biomaterial. Motalleb R, Berns EJ, Patel P, Gold J, Stupp SI, Kuhn HG. J Tissue Eng Regen Med. 2018, 12(4), e2123-e2133. 
  7. Creating a stem cell niche in the inner ear using self-assembling peptide amphiphiles. Matsuoka AJ, Sayed ZA, Stephanopoulos N, et al. PLoS One. 2017, 12(12), e0190150. 
  8. Measuring Drug Metabolism Kinetics and Drug-Drug Interactions with SAMDI Mass Spectrometry.  Anderson, L., Berns, E., Bugga, P., George, A. and Mrksich, M.  Anal. Chem., 2016, 88, 8604-8609. [PDF]
  9. A tenascin-C mimetic peptide amphiphile nanofiber gel promotes neurite outgrowth and cell migration of neurosphere-derived cells. Berns EJ, Álvarez Z, Goldberger JE, et al.  Acta Biomater, 2016, 37, 50-58.
  10. Cellular Assays with a Molecular Endpoint Measured by SAMDI Mass Spectrometry.  Berns, E.J., Cabezas, M.D., and Mrksich, M. Small, 2016, 12, 3811-3818. [PDF]
  11. Aligned neurite outgrowth and directed cell migration in self-assembled monodomain gels. Berns EJ, Sur S, Pan L, et al. Biomaterials. 2014, 35(1), 185-195.
  12. β1-Integrin and integrin linked kinase regulate astrocytic differentiation of neural stem cells. Pan L, North HA, Sahni V, et al. PLoS One. 2014, 9(8), e104335. 
  13. A bioengineered peripheral nerve construct using aligned peptide amphiphile nanofibers. Li A, Hokugo A, Yalom A, et al. Biomaterials. 2014, 35(31), 8780-8790.
  14. Supramolecular Nanofibers of Peptide Amphiphiles for Medicine. Webber MJ, Berns EJ, Stupp SI. Isr J Chem. 2013, 53(8), 530-554.
  15. Nanofiber-mediated inhibition of focal adhesion kinase sensitizes glioma stemlike cells to epidermal growth factor receptor inhibition. Srikanth M, Das S, Berns EJ, Kim J, Stupp SI, Kessler JA. Neuro Oncol. 2013, 15(3), 319-329.
  16. Electrostatic control of bioactivity. Goldberger JE, Berns EJ, Bitton R, Newcomb CJ, Stupp SI. Angew Chem Int Ed Engl. 2011, 50(28), 6292-6295. 

Justin Modica

Justin’s Publications:

Postdoctoral Researcher Since 2012

 

 

 

  1. Design and Synthesis of Megamolecule Mimics of a Therapeutic Antibody. J. Modica, T. Iderzorig, M. Mrksich J. Am. Chem. Soc., 2020 [PDF]
  2. Solid-Phase Synthesis of Megamolecules.  B. R. Kimmel, J. A. Modica, K. Parker, V. Dravid and M. Mrksich  J. Am. Chem. Soc., 2020, 142, 4534-4538. [PDF]
  3. Long-Range Energy Transfer in Protein Megamolecules.  E.L. Taylor, K.J. Metcalf, B. Carlotti, C.-T. Lai, J.A. Modica, G.C. Schatz, M. Mrksich and T. Goodson.  J. Am. Chem. Soc.,  2018, 140, 15731-15743. [PDF]
  4. An Immobilized Enzyme Reactor for Spatiotemporal Control over Reaction Products. Grant, J., Modica, J.A., Roll, J. Perkovich, P. and Mrksich, M. Small, 2018, 14. [PDF]
  5. Synthesis of Cyclic Megamolecules.  Modica, J.A., Lin, Y. and Mrksich, M.  J. Am. Chem. Soc., 2018, 140, 6391-6399. [PDF]
  6. Acid-Resistant Mesoporous Metal-Organic Framework toward Oral Insulin Delivery: Protein Encapsulation, Protection, and Release. Chen Y, Li P, Modica JA, Drout RJ, Farha OK. J Am Chem Soc. 2018, 140(17), 5678-5681.
  7. Toward Design Rules for Enzyme Immobilization in Hierarchical Mesoporous Metal-Organic Frameworks.  Peng, L., Modica, J.A., Howarth, A.J., Vargas, E., Moghadam, P.Z., Snurr, R.Z., Mrksich, M., Hupp, J.T. and Farha, O.K.  CHEM, 2016, 1, 154-169. [PDF]
  8. A Self-Adjuvanting Supramolecular Vaccine Carrying a Folded Protein Antigen. G. A. Hudalla, J. A. Modica, Y. F. Tian, J.S. Rudra, A. S. Chong, T. Sun, M. Mrksich and J. H. Collier.  Adv. Healthcare Mater.2013, 2, 1114-1119. [PDF]
  9. Modular Assembly of Protein Building Blocks to Create Precisely-Defined MegaMolecules. J. A. Modica, S. Skarpathiotis and M. Mrksich.  ChemBioChem  2012, 13, 2331-2334. [PDF]
  10. A Conformation- and Ion-Sensitive Plasmonic Biosensor. W. Hall, J. Modica, J. Anker, Y. Lin, M. Mrksich and R. Van Duyne.  Nano Letters  2011, 11, 1098-1105. [PDF]
  11. A Calcium-Modulated Plasmonic Switch. W.P. Hall, J.N. Anker, Y. Lin, J. Modica, M. Mrksich and R. P. Van Dyne, J. Am. Chem. Soc. 2008, 130(18), 5836-5837. [PDF]
  12. Dynamic Hydrogels: Translating a Protein Conformational Change to Macroscopic Motion. W.L. Murphy, W.S. Dillmore, J. Modica and M. Mrksich,  Angew. Chem.,  2007,  46, 3066-3069.  [PDF]

Adam Pluchinsky Adam Pluchinsky:

Ph.D. Student Since 2016

 

 

 

  1. High Throughput Screening with SAMDI Mass Spectrometry for Directed Evolution. A. J. Pluchinsky, D. W. Wackelin, X. Huang, F. H. Arnold, M. Mrksich  J. Am. Chem. Soc., 2020, 142, 19804-19808. [PDF]
  2. Modular Assembly Approach to Engineer Geometrically Precise Cardiovascular Tissue. Lee BW, Liu B, Pluchinsky A, Kim N, Eng G, Vunjak-Novakovic G. Adv Healthc Mater. 2016, 5(8), 900-906.

Dan SykoraDan’s Publications:

Ph.D. Student Since 2017

 

 

 

  1. Using Peptide Arrays to Profile Phosphatase Activity in Cell Lysates. L. C. Szymczak, D. Sykora and M. Mrksich  Chem. Eur. J. 2020, 26, 165. [PDF]

Sraeyes SridharSraeyes’ Publications:

Ph.D. Student Since 2018

 

 

 

  1. Modulating local S1P receptor signaling as a regenerative immunotherapy after volumetric muscle loss injury. Hymel LA, Ogle ME, Anderson SE, et al. J Biomed Mater Res A. 2020 (Online)
  2. Monocytes and Macrophages in Heart Valves: Uninvited Guests or Critical Performers? Sraeyes S, Pham DH, Gee TW, Hua J, Butcher JT. Curr Opin Biomed Eng. 2018, 5, 82-89.
  3. Monocytes and macrophages in tissue repair: Implications for immunoregenerative biomaterial design. Ogle ME, Segar CE, Sridhar S, Botchwey EA. Exp Biol Med (Maywood). 2016, 241(10), 1084-1097.